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    10 results
  • https://pubmed.ncbi.nlm.nih.gov/38491519/
    The rise of big data: deep sequencing-driven computational ...

    Mar 16, 2024 ... The rise of big data: deep sequencing-driven computational methods are transforming the landscape of synthetic antibody design. J Biomed Sci ...

  • https://pmc.ncbi.nlm.nih.gov/articles/PMC5203765/
    Deep sequencing and human antibody repertoire analysis - PMC

    Apr 8, 2016 ... In the past decade, high-throughput DNA sequencing (HTS) methods and improved approaches for isolating antigen-specific B cells and their ...

  • https://pubmed.ncbi.nlm.nih.gov/33008118/
    Expansion and Refinement of Deep Sequence-Coupled Biopanning ...

    Sep 30, 2020 ... We previously reported a technology that couples deep sequencing technology with a bacteriophage MS2 virus-like particle (VLP) peptide display platform.

  • https://www2.mrc-lmb.cam.ac.uk/new-deep-screening-technique-enables-rapid-discovery-of-high-affinity-antibodies-to-clinically-relevant-drug-targets/
    New deep screening technique enables rapid discovery of high ...

    Oct 9, 2023 ... Leveraging next generation sequencing technology, deep screening promises to accelerate antibody discovery for a wide range of targets by ...

  • https://www.nature.com/articles/s41551-023-01093-3
    Rapid discovery of high-affinity antibodies via massively parallel ...

    Oct 9, 2023 ... The method, which we named 'deep screening', involves the clustering and sequencing of antibody libraries, the conversion of the DNA clusters ...

  • https://www.sciencedirect.com/science/article/pii/S1871678424000037
    Deep mining of antibody phage-display selections using Oxford ...

    May 25, 2024 ... We introduce a high accuracy long-read sequencing method based on the recent Oxford Nanopore Technologies (ONT) Q20 + chemistry in combination with dual unique ...

  • https://www.nature.com/articles/s41598-023-45538-w
    Insights into next generation sequencing guided antibody selection ...

    Oct 26, 2023 ... An integrated technology ... Optimization of therapeutic antibodies by predicting antigen specificity from antibody sequence via deep learning.

  • https://jbiomedsci.biomedcentral.com/articles/10.1186/s12929-024-01018-5
    The rise of big data: deep sequencing-driven computational ...

    Mar 16, 2024 ... The rise of big data: deep sequencing-driven computational methods are transforming the landscape of synthetic antibody design. Eugenio Gallo ...

  • https://www.pnas.org/doi/10.1073/pnas.1403278111
    Antibody repertoire deep sequencing reveals antigen-independent ...

    Jun 9, 2014 ... This discovery, enabled by sequencing technology and mathematics, adds a surprising new dimension to our understanding of antibody repertoires, ...

  • https://www.nature.com/articles/s41467-023-38063-x
    Fast, accurate antibody structure prediction from deep learning on ...

    Apr 25, 2023 ... 1: Diagram of method for end-to-end prediction of antibody structures. figure 1. Antibody sequences are converted into contextual embeddings ...

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  • Antibody De Novo Sequencing

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